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Collagen type I, a major protein of the extracellular matrix (ECM) in mammals, is a suitable scaffold material for regeneration.
Objective: We have previously demonstrated that collagen I, a major component of postoperative adhesions, is differentially regulated in fibroblasts isolated from normal human peritoneum and adhesions.
Synapsin I, a major component of synaptic vesicles, is known to be up-regulated by LTP in the dentate gyrus [14], and its transcription, which can be regulated by BDNF, is also associated to different degrees of learning [15] [16].
L-BOAA causes GSH loss and increase in protein-glutathione mixed disulfides (PrSSG) in lumbosacral cord of male mice [3] resulting in selective inhibition of mitochondrial complex I, a major component of the mitochondrial electron transport chain, due to oxidation of critical thiol groups [13].
The vignettes involved either (i) a major depressive disorder; (ii) a major depressive disorder and suicidal thoughts; (iii) early schizophrenia; or (iv) chronic schizophrenia (see Appendix).
Collagen I, a major constituent of the sub-mesothelial ECM [ 26], is the preferred substrate for ovarian cancer cell attachment [ 40] and migration [ 37, 41].
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