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Bishop and Lowell's correspondence is substantially more significant in its actual status as a correspondence between friends and literary peers than in its hypothetical status as romantic love.
The shift to "Rules" and "Phenomena" in the second edition clarified the logical structure of the derivation of the law of universal gravity and removed any thought that this derivation gave the law an only hypothetical status.
The hypothetical status of all physical theories is underscored also in Some Thoughts Concerning Education: "The systems of natural philosophy…are to be read, more to know the hypotheses…than with hopes to gain thereby a comprehensive, scientifical, and satisfactory knowledge of the works of nature".(Locke, quoted in Rogers 1982, p. 230).
However, it is also interesting that a larger number of genes upregulated in cBF encode proteins with hypothetical status (conserved or T. brucei-specific) that have signal sequences.
Of the 42 ORFs 28 were of hypothetical status, of which, 17 contained no homology with an entry in the NCBI nucleotide database (accessed on 1/10/12).
The SPI-23 of S. Dublin CT02021853 and S. Gallinarum SGG1 contains four unique genes that are not of hypothetical status.
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In all cases almost a quarter of the genome annotation was found to be of hypothetical gene status.
One key finding is that the most used choice task format in environmental economics, i.e., two hypothetical and a status quo alternative, is likely to increase the propensity to choose the status quo option.
Respondents rated their likelihood of following the hypothetical patient's DNR status on a 5-point scale.
Three genes/probe sets were also excluded because of their status as hypothetical proteins (KIAA0101, KIAA0776, KIAA1467).
Therefore, further investigations are necessary to clarify this hypothetical correlation between MSI status and the expression of the tumour suppressor SASH1.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com