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We propose that the object D-factor, as yet a hypothetical factor, is the instrument that governs the Checkpoint process.
Therefore, we extend the core network of Oct4, Sox2 and Nanog by adding a hypothetical factor X (compare Materials and Methods).
Whether this hypothetical factor is still on the increase or has passed its peak is unknown.
This mechanism is supported by experimental results although the hypothetical factor has not been identified [ 27, 28].
As per the hypothetical factor structure originally proposed by Ware, Kosinski and Keller [ 38], orthogonal models were evaluated for both solutions.
In what follows, we use stochastic modelling to examine the contributions of both ternary complex and the hypothetical Factor X on GCN4 control.
Similar(51)
The two hypothetical factors of the goalkeeper-model should correspond to events during embryonic or larval development.
If this conjecture proves correct, it will be important to identify the proteases responsible for cleavage of PrPC, here termed α-PrPases, and any hypothetical factors that may control their activity.
Regarding biomarker approaches, two main hypothetical factors for analysis can be opted: firstly, the investigation of proteins specifically related to microbial pathogenicity like secreted/surface or immunogenetic proteins, as often performed by protein-biochemical methods.
Our objective is to consider the mix of hypothetical factors that may affect the detection of epidemics attributable to CDC category A bioterrorism agents (11 ).
These hypothetical factors are likely to change during the following years and decades as a consequence of external pressure on health systems.
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