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We used a decision-analytic model of pneumococcal disease incidence and outcomes to assess the impact of current US pneumococcal vaccination practices on pneumococcal disease burden during both an annual influenza epidemic and a severe influenza pandemic, relative to the hypothetical burden if no pneumococcal immunization program had been implemented.
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The effect of three hypothetical scenarios on the future burden of disease in 2030 was tested: baseline scenario, BMI trends go unchecked; intervention 1, population BMI decreases by 1%; intervention 2, BMI decreases by 5%.
The first would be to use the actual 2006 tax burden instead of hypothetical tax revenue as the baseline for this summer's AMT bill.
To this end models for the number distribution [ 29] and size distribution [ 31] of hematogenous metastases will be utilized here to simulate the metastatic burden within a hypothetical series of identical cancer patients.
Exploratory factor analysis supported the hypothetical domains Injection-site reaction burden and Device features, with the exception of item 14 in the latter domain (concerning ability to administer the injection without help), which correlated with more than one factor.
To come up with a misery index for investment taxes, we chose a method that is arbitrary but not unfair: We scored tax burdens on three hypothetical married couples, then added the scores.
PIF has been extensively used in research to measure potential gains in mortality and burden of diseases under hypothetical counterfactual scenarios of elimination or reduction of risk factors related to the outcome of interest [ 17- 21].
Under conditions of alcohol dependence, the allostatic load a hypothetical measure of cumulative stress increases and burdens the organism with excessive exposure to stress hormones and peptides as well as pro-inflammatory cytokines (McEwen 2007).
To reduce the burden on the patient in responding to multiple hypothetical treatment comparisons, each patient reviewed 12 comparison cards.
A regiment stuck in coastal God-knows-where defending against a hypothetical invasion that never comes is, in some ways, a bigger burden than if they'd just been killed outright.
The total burden of 100% (single) use of rosuvastatin in a hypothetical cohort of 100 patients was €1.07 million versus €1.13 million for atorvastatin, €1.17 million for simvastatin, and €1.19 million for pravastatin.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com