Sentence examples for hypothesized to involve the from inspiring English sources

Using molecular modeling, the mechanism of action was hypothesized to involve the chelation of the divalent metal ions inside the IN active site.

The transformation of an abstract phonological code into articulation has been hypothesized to involve the retrieval of stored syllable-sized motor plans.

The cGMP-dependent activation of AQP1 ion channels was hypothesized to involve the carboxyl (C -terminus [ 9].

A biologic mechanism for post-immunization GBS has been hypothesized to involve the synergistic effects of endotoxins (the product of Salmonella contamination) and vaccine-induced autoimmunity [ 30].

This process is hypothesized to involve the cutting of transposon transcripts by Piwi/Aub-bound antisense piRNAs and the loading of resultant sense piRNAs onto Ago3.

Activation of the AQP1 ion conductance by intracellular cGMP was hypothesized to involve the carboxyl (C-) terminus, based on amino acid sequence alignments with cyclic-nucleotide-gated channels and cGMP-selective phosphodiesterases.

The exact mechanism by which mutant SOD1 eludes ERAD remains unknown but it has been hypothesized to involve interfering with the final transfer of ubiquitin to the misfolded protein by the E3 ligase (Le Pecheur et al., 2005; Nishitoh et al., 2008).

Both TD and ADHD have been hypothesized to involve dysfunction in the CSTC circuits [ 2, 9, 10].

The mechanisms by which these factors increase cancer risk have been hypothesized to involve insulin and the insulin-like growth factor axis, which are intimately involved in glucose and energy homeostasis (Kaaks and Lukanova, 2001; Jerome et al, 2003).

The μ-opioid receptor-mediated depression of XII MN inspiratory output is hypothesized to involve ACh release and the subsequent presynaptic inhibition of glutamatergic transmission through activation of muscarinic receptors [24], however, this finding is controversial [2].

Emotional dysregulation is often hypothesized to involve some deficit in the ability to modify emotional responses as a result of underlying neurobiological dysfunctions and/or temperament traits [ 31].