We hypothesized that this requirement for T cell activation could be leveraged to express marker genes within activated T cells responding to antigen-pulsed dendritic cells and allow for the selective enrichment and modification of antigen-specific T cells.
We hypothesized that the requirement for high-dose ESA therapy in some anemic CKD patients may be associated with elevated inflammatory markers and/or impaired nutritional status.
These findings could indicate that SAG requires additional signaling partners to be effective within corpus callosum cells, akin to the requirement hypothesized for blood brain barrier disruption for the Shh conversion of cortical astrocytes into neural stem cells (Sirko et al., 2013).
Although none of the perceived treatment consequences were associated with change in A1C or insulin requirements, as hypothesized, each perceived consequence was associated with a corresponding clinical outcome (Table 2 A F).
It has been hypothesized that the molecular requirements for semen samples able to achieve a pregnancy differ for each type of assisted reproduction procedure, and there are fewer molecular requirements when the reproductive techniques are more invasive, such as ICSI, meaning that the machinery needed for sperm function is minimal (Garrido et al., 2013).
As blooms are also grazed by zooplankton such as copepods that are able to swim over large distances seeking phytoplankton patches to fulfill their nutritional requirements, we hypothesized that they can act as transmission-vectors enhancing viral dispersal within and across water masses at sea.
Based on other protein requirements for active transport, we hypothesized that PTEN would require ATP for its nuclear-cytoplasmic shuttling.
We hypothesized that a longer requirement for vasoactive drugs, even with a higher RIFLE class, is a variable concerning the perioperative drug management of patients, and could be a surrogate marker of unresolved postoperative cardiac or vascular dysfunction.
As p27 is a potent suppressor of the G1/S transition and activator of apoptosis, we hypothesized that the known requirement of PFKFB3 for cell cycle progression and prevention of apoptosis may be partly due to the ability of F2,6BP to activate Cdks.
Based upon other proteins' requirement for active transport (34– 37), we hypothesized that PTEN would require ATP for nuclear import.
Thus it is reasonable to hypothesize that the requirements for HCF-1 to promote cell-cycle progression are more relaxed in HeLa cells.
