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Thus, TN-C promoted epithelial cell proliferation leading to luminal filling, a process that we hypothesized involved c-met, a proto-oncogene amplified in breast tumors that promotes intraluminal filling.
From our microarray analysis in AP-2α silenced GN-11 neurons and AP-2α knock-out MEFs we learned that a large group of genes, much larger than we hypothesized, involved in cell growth and/or cell movement is modulated by AP-2α.
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Increasingly the mechanisms hypothesized involve non-sequential organization of non-linear operations and so exceed the ability of researchers to mentally rehearse their behavior.
Alternately, a purely linguistic activation could be hypothesized, involving the Visual Word Form Area (left fusiform gyrus of the temporal cortex) being more responsive to (equally frequent) more salient or arousing words [33], [34].
We attribute the production of labeled formate from C-3 as the result of the cleavage of the β-carbon of 3-hydroxypropionate, which we hypothesize involves a spontaneous retro-aldol type of reaction (Supplementary Figure 2).
l(2 gl, which has been recently hypothesized as involved in the CI mechanism [ 6], is also up-regulated.
The major neurotransmitter hypothesized as involved in delirium is acetylcholine, and the major neuro-anatomical area is the reticular formation [ 2].
Interestingly, the sensitivity of the reward system is hypothesized to involve dopaminergic projections (Urosevic et al. 2008) which are also involved in the neurobiology of both substance and behavioral addictions (Grant et al. 2006).
The aetiology of asthma pathology is complex and highly heterogeneous, involving the interplay between genetic and environmental risk factors that is hypothesized to involve epigenetic processes.
Using molecular modeling, the mechanism of action was hypothesized to involve the chelation of the divalent metal ions inside the IN active site.
The transformation of an abstract phonological code into articulation has been hypothesized to involve the retrieval of stored syllable-sized motor plans.
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