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All data operations and tests of hypothesis were performed using SAS 9.3 for Windows (SAS Institute).
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The validation of this hypothesis is performed by simulations of the reaction diffusion system in a representative tridimensional unit cell, coupled with a model of scaffold degradation by hydrolysis.
The quantitative evaluation of the probability that the observed correlation between LOD changes and volcanic eruptions may derive from a random pattern (null hypothesis) was performed through the Monte Carlo method.
An important analysis of the array treadmilling hypothesis was performed by Mogilner and Edelstein-Keshet [ 412] on the basis of a deterministic microscopic model.
To identify this, a conjunction analysis (conjunction null hypothesis) was performed at the second (between-subject) level (Friston et al. 2005).
Testing of the neutral mutation hypothesis was performed by calculating the Tajima's D value using the DNAsp program (http://www.ub.edu/dnasp/).ub.edu/dnasp/
All analyses were performed using R software [ 21], multiple imputation was performed using the mice R package [ 22], and multiple imputation under MNAR hypothesis was performed using the SensMice R package [ 19].
Tests of hypotheses were performed at a 2-sided significance level of 5%.
Furthermore, the a priori hypotheses were performed at one point in time, at baseline.
Calculations for the corresponding null and alternative hypotheses were performed using the codeml program implemented in the PAML package [ 16].
All of the analyses were completed for each of the five studies individually, and tests of hypotheses were performed at a two-sided significance level of.05.
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CEO of Professional Science Editing for Scientists @ prosciediting.com