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To reduce noise and to see if our hypothesis was applicable to a greater range of CTL epitopes (not just the 21 at which CTL escape had been described) we calculated the Shannon entropy of all confirmed CTL epitopes from the LANL database defined to within 11 amino acids that did not overlap with other epitopes presented by alleles with a different relative hazard.
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Simulation models based on field research with plague and prairie dogs revealed that the first hypothesis is applicable because the prairie grasshopper mouse (Onychomys leucogaster), which overlaps geographically with prairie dogs and on which flea density increases during plague epidemics.
As a preliminary step to investigate whether this hypothesis is applicable to lung carcinomas, it is necessary to identify and isolate cancer initiating cells using suitable markers.
To investigate whether the hypothesis is applicable to lung cancer, identification of lung CSC and demonstration of these capacities is essential.
Although colour-marking polymorphisms are not rare, empirical evidence remains limited for which hypothesis is applicable to real organisms in the wild.
A similar hypothesis has been proposed to explain the impact of Nosema ceranae on colonies [15], but we argue this hypothesis is applicable to any factor that chronically elevates forager bee death rates.
This hypothesis is applicable to the effects of c-PAHs.
We examined whether this hypothesis is applicable to humans.
Whether the combination hypothesis is applicable in Canna needs broader investigation.
Marsupials can be used as a model to test whether this hypothesis is applicable for non-primate mammals.
Whether the TW hypothesis is applicable to polytocous species (species that produce several offspring per litter) is unclear (Williams 1979).
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