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This hypothesis was analyzed using T CD4+ cells isolated from the spleen of OT-II mice, which bear a transgenic αβ T cell receptor specific for the MHC class II-restricted OVA 323 339 peptide.
This hypothesis was analyzed in the current study using a combination of preliminary expression screening in 19 different types of epithelial tumors with commercial microarrays (altogether 395 informative samples, Table 1) and evaluation of the CHL1 mRNA expression in primary tumors using RT-qPCR.
This hypothesis was analyzed biochemically by immunoblot.
The study employs multiple hypothesis testing, where each hypothesis was analyzed separately and the existence of patterns in results and the consistency of the results were considered in the analysis [ 25, 26].
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The posterior weights of the possible topologies of each quartet under each hypothesis were analyzed using the quartet puzzling algorithm.
hypotheses were analyzed through covariance analysis test.
The aforementioned hypotheses were analyzed using a fixed-sequence testing procedure.
Two different hypotheses are analyzed to explain the origin of the trace fossils; the less probable one is that the structures are laminar calcretes associated with rhizoliths and rhizoconcretions.
The three alternative hypotheses were analyzed in order to cover the possibilities of any change, increase or decrease in the association score.
Differences in log likelihood values between null and alternative hypotheses were analyzed using the Likelihood Ratio Test (LRT) and the resulting values compared to appropriate chi squared values to determine significance, using a confidence threshold of p < 0.05 and df = 1.
To test this hypothesis, nociception was analyzed in EAE mice before the onset of clinical scores and during remissions.
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