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The central Gansu-Silk Road migration hypothesis (route C in Figure 1) has important implications for interpreting the close similarity and dearth of diversity among 19th century P. t. virgata and in modern P. t. altaica since behavioral and geographic factors may have interacted to produce mitochondrial invariability in the common ancestor of the two subspecies.
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Contrary to our hypothesis, driving route did not influence ADHD performance (speed, speeding, variance of speed) or eye movements or fixation duration, differently from control subjects.
For hypothesis testing, route of exposure may not be of central importance, but for hazard assessment, risk assessors typically require that studies use a route of exposure that is deemed "relevant" to humans [ 57].
These methods provide clear, hypothesis-driven routes to solve problems that plague many proteins and to create novel mechanisms of action.
A detailed study would be needed to assess the adequacy of the diagnostic hypotheses and routes of administration.
As such, spatial patterns can be used to examine hypotheses on routes of transmission at different scales [ 1- 3].
By superimposing monthly Salmonella hospitalizations onto maps of ambient temperatures and livestock abundances, dynamic maps can be used to generate hypotheses about routes of exposure, spatial patterns of transmission, and diseases clustering.
The results presented here indicate that the age-specific incidence data for most human carcinomas is consistent with the parallel route hypothesis as expressed in Equations 3 and 4. The parallel routes hypothesis, then, implies (through the age specific-incidence data) that only a subset of the population is susceptible to developing each carcinoma.
The parallel route hypothesis is consistent with the colon carcinoma age-specific incidence data, while the multi-stage hypothesis is not.
Thus, this data supports the hypothesis that the route of infection does affect the rate of SIV evolution.
This approach has already provided relevant results to understand the peopling history of specific geographic regions (Currat et al. 2010) and is currently being applied to East Asia to test the "southern route" hypothesis versus the "pincer" or "overlapping" models (Di et al. (2011) In prep.
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