I think, even to start, you have to have some sort of working hypothesis; you have to have kind of an idea.
"Based on just these objective tests, what kind of working hypothesis would you be looking at?" Willmott asked.
This type of working hypothesis cannot be generated using conventional theoretical flux analysis because it requires that the modification systems that control enzyme activity be taken into account.
According to the working hypothesis of this work, rare motifs carry specific functions.
She has had more than her share of working hypotheses over the past 20 years: leukemia, lupus, rheumatoid arthritis, ankylosing spondylitis, celiac disease, ulcerative colitis, Crohn's disease.
The first one demonstrates the effect of working hypotheses on design outputs of an open caisson of 22 m internal diameter.
The models were developed on a combination of working hypotheses, designed to extend their predictive ability to multiple phenological events, i.e. budburst, flowering and veraison.
We have also developed data mining and visualization tools for the generation of working hypotheses (KaPPA-View and RnR).
This characteristic makes computer models suited to perform "what-if" analyses to elucidate relationships between different phenomena and to aid in the validation or rejection of working hypotheses.
"On pragmatistic principles," James writes, "if the hypothesis of God works satisfactorily in the widest sense of the word, it is true" (143).
This finding supports the central hypothesis of this work – that transcriptional profiles (in the form of gene expression data) can be used to predict optimization schemes for translational regulation (in the form of codon optimization).
