Sentence examples for hypothesis of extensive from inspiring English sources

The lack of large trans effects in both sexes is consistent with the hypothesis of extensive pleiotropy.

Consistent with the hypothesis of extensive diversity in a single cell type, Friedländer et al. recently detected a total of 213 known miRNAs in a single HeLa sample [ 46].

Thus, the present results support the hypothesis of an extensive involvement of TLRs in neurodegenerative disorders, pointing to the development of neuroprotective therapies by targeting these TLR-mediated inflammatory mechanisms, including cytokine-induced neurotoxicity.

In our study, the hypothesis of whether this extensive lack of oncogenic mutations in our series could be attributed in part to an efficient MMR mechanism was investigated by focusing on the status of hMLH1 and hMSH2 proteins of the DNA mismatch repair system, which stabilize the genome and repair postreplicatively the mismatches and the small single stranded DNA loops [ 54].

The abortion breast cancer hypothesis has been the subject of extensive scientific inquiry, and the scientific community has concluded that abortion does not cause breast cancer and that breast cancer should not be a concern for women who are considering having an abortion.

Verification of the hypothesis requires extensive laboratory tests.

The gene content variation of phage-related genes in EHEC 2 strains supports the hypothesis that extensive modular shuffling of mobile DNA elements has occurred among EHEC strains.

Thus, the hypothesis of this study was that extensive prehospital volume replacement has a negative impact on patient mortality and represents an independent risk factor.

To further test this hypothesis, an extensive search for proteins of chlamydial origin was performed using several recently sequenced algal genomes and EST databases, and the proteins subjected to phylogenetic analyses.

However, in spite of extensive debate the validity of the 2R hypothesis remains controversial.

The leading hypothesis of this programme was that the extensive, active engagement of all HCW, added to the continuous monitoring and feedback to staff would have been essential to the success of the project.