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Specifically, we use it to find the minimal threshold of casualty numbers for which the hypothesis of equal distribution of the two datasets can not be rejected.
For eight families (Table S1), the hypothesis of equal distribution among habitats was tested and rejected (Chi-square test; p<0.01).
The Pearson's Chi-square test was used to test the hypothesis of equal distribution of ER expression in categorical variables (positive vs negative).
Pearson's chi-square two-proportion test was used to evaluate the hypothesis of equal distribution of molecular alterations in different clinic-pathological variables.
The hypothesis of equal distribution between these two groups would predict that, inside the NC probe sets of group C, NC*PG probe sets should be associated to the GO term.
The complete validation framework comprising the l1- l2 regularization is implemented in MATLAB code (available at ) We test the hypothesis of equal distribution of the probesets in the two different statuses by means of t-statistic.
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This effectively tested the hypothesis of equal distributions of three or more independent samples.
The Kolmogorov-Smirnov two-sample test showing the two-sided probability of exceeding the difference of two samples calculated under the null hypothesis of equal distributions.
The two-sided probability of exceeding the difference of two samples, p, is calculated under the null hypothesis of equal distributions.
Since outliers were detected, the null hypothesis of equal distributions was also tested non-parametrically using the Wilcoxon matched-pairs signed-ranks test.
The null hypothesis of equal distributions was, however, also rejected when using the non-parametric Wilcoxon matched-pairs signed-ranks test (p = 0.029).
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