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Since (alpha =0.01), values above 2 (dashed-line) indicate rejection of the null hypothesis of connectivity absence.
Comparison of exactly similar mechanisms across the three models supported the hypothesis of connectivity dominance where mechanisms classified as either fragile or robust in the G1/S and G2-DNA damage models were also predicted to be important in the Novak and Tyson model, albeit with different ranks (Table 4).
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Studies of functional and effective connectivity also support a hypothesis of abnormal connectivity within the network suggested here.
It is therefore of great importance to devise a method allowing to statistically validate whether a given link in the projected network is consistent or not with a null hypothesis of random connectivity between elements of the bipartite network.
Previous studies have proposed and verified the hypothesis of functional connectivity in regions-of-interest [ 28] and voxel-based analyses [ 29- 31].
The four models – panmixia, full migration, stepping-stone migration, and complete isolation – represent different hypotheses of population connectivity and can thus inform the topology of network models of dengue spread (Fig. 2).
To do so, causal modelling is often used to test different alternative hypotheses of landscape connectivity (Cushman et al. 2006) and least-cost paths are integrated in these models using habitat-specific costs to choose the most parsimonious model to explain the genetic distances documented among clusters or individuals.
The first-level DCM analysis allowed us to reject the hypothesis of direct effective connectivity from DLPFC to amygdala.
Our findings provide structural reconstruction in humans in vivo of the crossed-fibre pathways from cerebellar to cerebral cortex in accordance with predictions by ex vivo anatomical investigations (Voogd 2003; Standring 2008) and support the hypothesis of a prominent connectivity of lateral cerebellum to contralateral associative areas (Buckner et al. 2011).
Other evidence points to abnormalities in neural circuitry, leading to the "disease of connectivity" hypothesis [ 1].
What is common among the competing theoretical paradigms, such as Weick's and Granovetter's hypotheses, is the degrees of connectivity or extent of fragmentation between networking or potentially networking groups.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com