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We tested the hypothesis of changing HIV-1 virulence by examining trends in rate of progression of HIV-1 infection in men followed in the Multicenter AIDS Cohort Study (MACS) from 1984 to 2005.
We tested the hypothesis of changing HIV-1 virulence by examining trends in prognostic clinical markers of disease progression from 1984 to 2005 among nearly 400 antiretroviral-naïve participants in the United States Multicenter AIDS Cohort Study (MACS), a longitudinal study of HIV infection in men who have sex with men (MSM).
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The lack of sexual dimorphism in some dendrobatid populations suggests that sexual selection is not a valid hypothesis of the changing coloration.
To test this hypothesis, we studied the impact of changing VSD-pore interactions directly via a point mutation of KCNQ1, F351A.
Our findings also lend some additional support to the hypothesis that viruses have evolved mechanisms of changing the host cellular milieu to facilitate viral replication and pathogenesis strategies that can be investigated at a mechanistic level, and our data suggest additional avenues for the development of novel antiretroviral therapeutics.
We also devised a new index based on shifts in peak timing of monthly temperatures, to refine hypotheses for changing phenology.
Using these concepts, students develop hypotheses and test predictions regarding the impacts of changing climatic conditions on specific aspects of chipmunk biology.
Recent reports of changing epidemiology of leptospiral serovars in the Pacific region [ 21- 24] support the hypothesis that ecological factors are likely to be responsible for driving serovar emergence.
The ecological effects of changing relative abundance of community members have been explored extensively (e.g, the Janzen Connell hypothesis).
No way of changing bills.
It's changing things for the sake of changing them.
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