A small volume correction was performed based on our primary hypothesis, limiting our analysis to the hypothalamus.
Taken together, these results support both the developmental constraint hypothesis limiting the divergence of early expressed developmentally important genes, leading to a gradient of divergence rates over ontogeny (embryonic < larval/pupal < adult), as well as Darwin's 'selection opportunity' hypothesis leading to increased divergence in adults, particularly in the case of reproductive tissues.
Christoff and Gabrieli (2000) and Christoff et al. (2001, 2003) proposed that lateral rostral prefrontal cortex supports the manipulation of self-generated information, rather than, like the gateway hypothesis, limiting the role of this region to attending towards self-generated information.
Its cross-sectional design which, while it allows association studies and the generation of new hypotheses, limits the possible causal interpretation of the findings.
While the prior attributes hypothesis is well supported in the literature, current support for the social dynamics hypothesis is limited to experimental studies that artificially eliminate or minimize individual differences in fighting abilities.
A classic hypothesis proposes that circadian rhythm underlies the expression of photoperiodic diapause [ 58], although evidence supporting this hypothesis is limited [ 59, 60] and highly debated [e.g. [ 61]].
For youth, empirical evidence for any particular hypothesis remains limited.
Numerical simulations for Gold nano-structures illustrate that for certain configurations the violation of CB hypothesis is limited to those parts of the domain with severe surface effects.
Postcopulatory sexual selection is regarded as the likely evolutionary engine of this diversity [2], but direct support for this hypothesis is limited.
Existing first and second generation antipsychotic drugs based upon the dopamine hypothesis are limited by their inability to treat all symptom domains and their undesirable side effect profiles.
