This hypothesis lacks empirical support.
However, this hypothesis lacks experimental support and fails to explain the pemetrexed hypersensitivity observed in UNG−/− cells.
It has been proposed that the difference between the risk and the neutral haplotypes resides in interactions with other functional polymorphisms, such as the indel in exon 6, but this hypothesis lacks experimental support.
The phylogenies used, however, have generally been based on neighbor-joining algorithms and the resulting phylogenetic hypotheses have lacked support for most relationships.
The role of leaders is to quiz teams about their hypotheses and challenge their logic if those hypotheses appear to lack support.
Although this hypothesis lacks direct evidence, comparative analyses of the genome of D. stenobrocha provide support for this hypothesis.
Furthermore, the use of shorter sequences or a single gene generates phylogenetic hypotheses that are incongruent or lacking support [ 55- 58], and increasing sequence length may be a better way to improve support, resolution, and accuracy of a difficult phylogeny (> 5000 bp in Hillis [ 59]; > 10,000 bp in Wortley et al. [ 60]).
Attempts to shed light on this subject using morphological traits have led to hypotheses lacking satisfactory statistical support; it seemed therefore that a different approach was needed.
In line with this hypothesis, lack of family support was found to be a barrier for both achieving (6) and maintaining (23) behavioral change in interventions for type 2 diabetes prevention.
Although these facts fit their model, their hypothesis still lacks direct experimental support.
In other words, our study found substantial variation in dewlap morphology and the hypotheses we tested lacked significant support because so much variation exists; increased variation would only render results less significant (where that is possible).
