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To test the hypothesis that inability to alter Htr2c RNA editing and splicing in INI mice reduces adaptation to the effects of chronic stress, mice were subjected to daily restraint for 20 consecutive days.
The present results are consistent with these physiological characteristics of the cough reflex and support the hypothesis that an inability to increase IAP predicts extubation failure.
Overall, our results are consistent with the hypothesis that the inability of sarA mutants to repress the production of extracellular proteases plays a predominant role with respect to their dominant-negative phenotype by comparison to agr.
A major problem regarding this hypothesis is the inability to link amyloid accumulation to the severity of the disease, and difficulty in demonstrating toxic forms of Aβ in AD brain.
6 One hypothesis for the inability of nutritional interventions alone to prevent a large share of growth faltering by age 24 months is that symptomatic and asymptomatic infections are important contributors to undernutrition.
This was supported by one-directional BN-PAGE, which confirmed a decrease in fully assembled complex II, consistent with the hypothesis that an inability to anchor the unstable complex within the mitochondrial membrane triggers the recycling of intermediates to prevent aggregation.
The most significant criticism of the hypothesis was its apparent inability to explain the Sun's relative lack of angular momentum when compared to the planets.
We therefore considered two alternative hypotheses to explain the inability to cluster.
The reconstruction of the Garki Project demonstrates the ability of models to aid in the understanding of previous campaigns and in separating out hypotheses for the historical inability to interrupt transmission despite intense pressure.
Existing first and second generation antipsychotic drugs based upon the dopamine hypothesis are limited by their inability to treat all symptom domains and their undesirable side effect profiles.
This "scavenging" hypothesis is confirmed by the inability of the parasite (the primary source of TXA2 during infection) to sustain TXA2 release in the COX-1 null mice.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com