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The retrospective and exploratory design of the present study, coupled with the non-randomized nature of the comparison between treated and untreated patients, imply that these results should be considered as hypothesis generators.
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Considering the complexity of the studied molecules, the hypothesis generator was restricted to select only five or less features.
Accordingly, our study might be viewed as a hypothesis generator and further trials are warranted to confirm the clinical relevance of our findings.
Some images contain the vehicle completely while others have been drawn to contain it only partially (all images contain at least 50% of the vehicle rear) in order to simulate putative results of the hypothesis generator.
The model is designed in such a way that one of the subsystems, namely, the Hopfield network, serves as the working memory and the other, the Hamming block, as the hypothesis generator.
In this context, the value of hypothesis generator research is to point out to putative pathways involved in this therapy.
Our work makes clear that expression profiles can be used as a powerful hypothesis generator for the study of organismal trait variation.
Thus, there is scope for a mathematical model that can explore mechanisms of TFV uptake and phosphorylation and act as a hypothesis generator for future experiments and models.
Owing to the inherent potential biases of such a subgroup analysis, this result can only be viewed as a hypothesis generator and should be confirmed in future studies.
We believe that our novel findings can serve as a hypothesis generator, supporting the utility to test CTCs as a predictive tool in larger randomized trials.
As in many other biomedical problem areas, a computational approach would here allow diverse experimental results to be absorbed into the formulation of the model, but more importantly, could serve as a hypothesis generator to test mechanisms through further experimentation.
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CEO of Professional Science Editing for Scientists @ prosciediting.com