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One hypothesis for the development of sensory profiles is that distinct pathophysiological mechanisms of pain generation produce specific sensory abnormalities.
We used terrain analysis and with cosmogenic nuclide measurements of erosion rates to quantitatively explore Wahrhaftig's decades-old hypothesis for the development of "stepped topography" by differential weathering of bare and soil-mantled granite.
These associations are compatible with the immune hypothesis for the development of mood disorders in at least a subgroup of mood disorder patients.
One hypothesis for the development of the aspherical femoral head is abnormal growth and lateral extension of the femoral head physis, with eccentric closure [21].
Based on the theoretical "two-hit hypothesis" for the development of transfusion-related ALI wherein neutrophils are initially primed by a risk factor (i.e., sepsis) and then activated by components of transfused blood [14, 30], patients with sepsis who are exposed to RBCs may be a population at increased risk for ALI after transfusion with blood of a long storage duration.
On another side, this study suggests new hypothesis for the development of antibacterial molecules acting as virulence inhibitors.
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Hypotheses for the development of smooth muscle atrophy include vasculopathy with resultant denervation, production of autoantibodies targeting smooth muscle and/or entrapment and destruction of smooth muscle by fibrosis [ 2].
Finally, is an 'infection hypothesis' plausible for the development of PLE in Fontan patients?
These investigations can be considered hypothesis generating for the development of properly powered randomised, prospective trials.
Such a prior hypothesis allows for the development of specialized methods with greater power to resolve differences among species or groups of species.
A reasonable hypothesis for the development and growth of HELUs is increased proliferation due to large increases in ER-α and PR, which are the receptors for these mitogens.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com