Exact(1)
Yet, FA could be very well used for gene selection when it is applied as an instrument to confirm what is expected on the basis of pre-established hypothesis (Confirmatory Factor Analysis, CFA) [ 11].
Similar(59)
However, FA can also be applied as an instrument to confirm what is expected on the basis of pre-established hypotheses (Confirmatory Factor Analysis, CFA).
It is recommended that future studies explicitly state in the Methods the exploratory (hypothesis-generating) or hypothesis-driven (confirmatory) nature of the experimental designs.
Since the early 1960-1970s, researchasas questioned the role of B. pertussis and its toxin in the hyper-eosinophilia response to pertussis [ 30- 32], but the hypothesis awaits confirmatory data from other studies and research.
One way to address the lack of a true gold standard was to conceptualize pain as a latent variable (one that cannot be observed) and use the results of the present exploratory factor analysis to generate hypotheses for confirmatory factor analysis [ 27, 31].
Barr, D. J., Levy, R., Scheepers, C. & Tily, H. J. Random effects structure for confirmatory hypothesis testing: Keep it maximal.
Maximal LMEMs should be the 'gold standard' for confirmatory hypothesis testing in psycholinguistics and beyond.
Also, as recommended for confirmatory hypothesis testing62, all models included the maximal random effects structure (as long as no convergence issues were encountered).
Here, we argue that researchers using LMEMs for confirmatory hypothesis testing should minimally adhere to the standards that have been in place for many decades.
In GWA studies, a finding is considered to be "replicated" if and only if there is an initial finding which did appropriately control for multiple testing with strong control of the family-wise type I error rate (FWER) and in a second independent sample this finding is re-detected in a confirmatory hypothesis testing setting [2].
No confirmatory hypothesis testing was planned or performed.
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