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According to Biology Direct: Hypothesis should present an untested original hypothesis backed up solely by a survey of previously published results rather than any new evidence.
Authors' response: According to the « Instructions for Biology Direct authors » (http://www.biology-direct.com/authors/instructions/hypothesis ), « hypothesis articles should present an untested original hypothesis backed up solely by a survey of previously published results rather than any new evidence.
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Part of the hypothesis is backed by our previous studies on the effect of the imposed substrate vibration on topography and nano-structure of spray-on films.
Scott-Railton said that — alongside the type of targets — the hypothesis is backed by the level of resources at the ring's disposal, its willingness to make threats, and its apparent lack of concern about being tracked down.
This hypothesis is backed by the similarity on both the protein level and the similarity of the binding sites.
The glutamate hypothesis is backed up by genetic evidence implicating proteins involved in glutamatergic function, including d-amino acid oxidase (DAAO), G72, and neuregulin 1 (NRG1) with schizophrenia (reviewed in ref (130)).
One reform suggested by many people to counteract publication bias would be to encourage the publication of more "negative findings" – papers where a hypothesis was not backed up by the experiment performed.
From the existence of these strains it can be concluded that C. glutamicum has the capability to produce significant amounts of sulphur-containing amino acids, a hypothesis that is backed at least for L-methionine by in silico studies [ 5].
This hypothesis is further backed by the finding that McbR was found to be conserved in all completely sequenced Corynebacteriaceae [ 29] which is in accordance with the high degree of conservation of the cluster in C. glutamicum, C. efficiens, and C. jeikeium.
These hypotheses were additionally backed by the experimental evidence that elemental analysis (by ICP -OES) of the solutICP -OESe revealed nofappreciable Cu in the solutionant after NCs phasepitated frevealedsolutiono therefore, even if Cu+ ions were releappreciableution, they were unstable there and tended to reaCu winh the Cusupernatantns.
The fly hypothesis needs to be backed by further experimental and epidemiological studies.
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