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The enormous potential for microarray studies to generate biologically relevant, mechanistic hypotheses of development is beautifully confirmed by studies such as these [ 1, 2].
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Such models can become a community-wide effort to integrate data and hypotheses of key development processes.
So why is the cancer research community continuing to be dominated by the dysfunctional tradition of employing mouse models to test hypotheses for development of new drugs?
Finally, apprentices should be engaged in the higher-order practices of research, including analysis of data, generation of hypotheses, and development of research questions.
► Hypothesis for development of Alzheimers disease.
To point out possible discrepancies in the classic hypothesis of Müllerian development and to present cases that support an alternative hypothesis.
According to the "vascular hypothesis of lung development," endothelial cell signaling is a crucial pre-requisite for the formation of the alveolar structure [30].
This observation makes a somewhat hypothetical connection to a concept presented 150 years ago by Rudolf Virchow [42] and Julius Conheim [43], who proposed the "embryonic rest hypothesis of cancer development" [44].
Furthermore, consistent with the hypothesis of aneuploidy development via unstable tetraploidy intermediates, cancer cells with chromosomal instability show the characteristics of continuous alteration in chromosomal status, highlighting the question for the initiation and the induction of tetraploidy.
The most widely accepted hypothesis of NPC development and progression involves a series of sequential steps.
Thus, we investigated the pathogenicity of Campylobacter through a cohort study and assessed the hypothesis of the development of immunity after Campylobacter infection in Madagascar.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com