Due to this open nature, GWAS does not require an initial hypothesis for exploring the genetic predisposing factors to a complex disease.
Before Digital Age, when experiments included only a handful of students, data science provided tools for designing experiments, for confirming or rejecting hypothesis and for exploring intermediate or latent patterns.
This paper describes ViVA's support for exploring hypotheses.
This paper proposes several hypotheses and research strategies for exploring possible psychological factors contributing to multiple chemical sensitivity (MCS).
The authors of the Ukrainian study commented that the apparent similarity between birth-month patterns for both types of diabetes has implications for exploring hypotheses based on shared etiological pathways.
The components resulting from the PCA are based on the observed variance and not on predefined hypotheses, making this technique suitable for exploring unknown relations between variables.
Whereas inductive models are useful for positing explanations of patterns observed in large amounts of data and when precise prediction is required, abductive models are useful for exploring mechanistic hypotheses and when uncertainty is pervasive [ 21],[ 27].
Obviously, violation of assumptions will impact the accuracy of these predictions, but a framework for making such null hypotheses provides a valuable tool for exploring the evolutionary forces that drive the diversification of microbial lineages.
Despite recent advances in genetics and imaging, the neurobiology of ASD remains largely obscure indicating that there is ample space for exploring new hypotheses regarding the etiological basis of the disorder [44].
