Sentence examples for hypertrophy model from inspiring English sources

For the in vitro hypertrophy model, Angiotensin II (AngII) treated cultured adult cardiac fibroblasts were used, whereas the in vivo hypertrophy model was generated by renal artery ligation in adult male Wistar rats (Rattus norvegicus).

This study aimed to investigate the role of false vocal folds (FVFs) medialization in phonation and the acoustic impact of ventricular hypertrophy by establishing an FVF hypertrophy model.

Here, we aimed at precisely analyzing the microRNA signature of cardiac hypertrophy and fibrosis by RNA sequencing in a standardized in vitro hypertrophy model based on engineered heart tissue (EHT).

In transverse aortic constriction-induced cardiac hypertrophy model in mice, the daily oral administration of KR-36996 (30 mg/kg) for 14 days significantly decreased left ventricular weight by 40% (P<0.05).

In our cardiac hypertrophy model, AMPK phosphorylation was increased by 64%.

Such increased PDE2 activity, without increased expression, has previously been reported in another rat cardiac hypertrophy model induced by abdominal aortic banding [12].

The anemia-induced cardiac hypertrophy models reported here are the first adult zebrafish cardiac hypertrophy models characterized.

For example, transgenic technology that has been widely used in mouse to generate cardiac hypertrophy models shall be adapted in zebrafish [8], [30].

However, since anemia can induce effects on the heart other than biomechanical, non-anemic zebrafish cardiac hypertrophy models shall be generated and characterized.

Postnatal inhibition of myostatin signaling in mice with diet-induced obesity will be necessary to directly compare these two muscle hypertrophy models to determine whether the reduction in adipose tissue mass in HFD-fed constitutively active Akt1 mice is caused by hypertrophy of fast glycolytic fibers, by increasing the activation of the Akt signaling pathways, or both.

TRPC3 expression is up-regulated in multiple rodent pathological cardiac hypertrophy models [ 4, 42].