For example, hyper-exposure to GH inhibits transcription of growth hormone releasing hormone (GHRH) mRNA while stimulating that of somatostatin (Bertherat et al 1993).
Both utricular and saccular otoliths (lapilli and sagittae, respectively) were significantly smaller after hyper-g exposure as compared to parallely raised 1g-control specimens and the absolute amount of otolith-Ca was diminished.
These results, combined with previous work, indicate that strong winds, hyper-aridity, exposure of friable Neogene strata, and ongoing rock deformation and uplift in the western Qaidam Basin have created an environment where wind, instead of water, is the dominant agent of erosion and sediment transport.
Subsequently, Hollingsworth and colleagues have demonstrated that mice deficient in TLR4 are protected against airway hyper-responsiveness after exposure to ozone.
We acknowledge that this interpretation is limited by the single time point examined, and further studies will be required before we can fully exclude the involvement of these pathways in the induction of airway hyper-responsiveness after exposure to particulate matter air pollution.
Signals were visualized by incubation of the membranes in ECL Plus reagents and exposure to Hyper performance Chemiluminescence film.
Signals were visualized by incubation of the membranes in Enhanced Chemiluminescence (ECL) Plus reagents and exposure to Hyper Performance Chemiluminescence film (GE Healthcare, Buckinghamshire, UK).
To determine exposure to hyper- and hypoglycemia using blinded continuous glucose monitoring (CGM) profiles in youth with type 1 diabetes (T1D) with residual β-cell function during the first year of insulin treatment.
It originally consists of spotted array measurements of 6152 genes in 173 experimental conditions that include temperature shocks, hyper and hypoosmotic shocks, exposure to various agents such as peroxide, menadione, diamide, dithiothreitol, amino acid starvation, nitrogen source depletion and progression into stationary phase.
After three washes with PBS, specific protein bands were detected with an enhanced chemiluminescence western blot detection system (ECL; Amersham Pharmacia Biotech, Little Chalfont, Bucks, UK), and detected after exposure to Hyper film ECL (Amersham Pharmacia Biotech, Little Chalfont, Bucks, UK).
The link between maternal and offspring obesity can be explained by the 'early-life hyper nutrition' pathway where exposure to over-nutrition during fetal or early postnatal life may lead to perturbations of adipogenesis and/or appetite control mechanisms, creating a propensity to later obesity [ 8].
