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Lead hybridization concept was used to design and synthesize twenty novel hybrid compounds by combining fungicidal leads viz.
Hybrid compounds with IL-8-release inhibition capabilities were identified.
Two series of novel pyrazolobenzothiazine-based hybrid compounds were efficiently synthesized starting from saccharin sodium salt.
This series of inorganic organic hybrid compounds exhibit variable supramolecular architectures.
We report on a series of hybrid compounds structurally derived from donepezil and AP2238.
We characterized the important structural parameters of the lipid peptide hybrid compounds for the antibacterial activities.
Ellman's assay revealed that the hybrid compounds showed moderate to potent inhibitory activity against the cholinesterases.
In vitro studies showed that these hybrid compounds showed good cholinesterase inhibitory activity.
The antioxidant activities of the hybrid compounds T2 T6 showed to be good in vivo.
A series of hybrid compounds were designed by structure-assisted and ligand-based strategies.
These phenylene-connected hybrid compounds were investigated as potential inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE).
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