When compared with the evidence-based, cost-effectiveness criteria underpinning most government reimbursement schemes in the social market economies, the three regulatory hurdles of safety, quality and efficacy are probably of modest impact in influencing increased usage of recombinant activated factor VII (rFVIIa; NovoSeven®, Novo Nordisk, Bagsvaerd, Denmark).
BETTER VIBRATIONS With magnetic tape, carmakers jumped the hurdle of bringing quality music recordings into the car.
At Cheltenham, meanwhile, the stage is set for a Champion Hurdle of such quality that it will set a benchmark for decades to come – until, perhaps, the Champion Hurdle of 2014.
As a result of these financial hurdles, the quality of food consumed is of little consideration.
While FMT has been established as a proof of principle for the feasibility of manipulating the human microbiome as a therapeutic strategy, the development of commercial products based on fecal transplants faces a number of hurdles from manufacturing, quality assurance, pathogen contamination risk, donor selection, and patient acceptance perspectives.
Time and cost are among the most often cited hurdles limiting the rate and extent of adoption of Quality by Design (QbD) and Process Analytical Technology.
Pamela Liebman, the president of the Corcoran Group, said one hurdle to a full recovery was a lack of quality inventory at all price points.
Although the general perception is that top-flight journals are loath to publish the results of quality improvement work, accumulating experience suggests that this hurdle can be overcome.
This finding is consistent with experience in low- and middle-income countries [ 17], and it highlights a fundamental hurdle in improving quality of care delivery in such settings.
The evaluation found that, once patients accessed the service (the first hurdle), quality of care was good in the TB programme but not in the HIV programme, possibly reflecting insufficient training coverage.
