Sentence examples for hurdle to effective from inspiring English sources
Advocates say the major hurdle to effective ammunition control a quarter century ago - laborious cross-referencing of criminal databases - has been made easier by technology.
Even in oncology, our very limited understanding of the oncogenesis of cancer is a major hurdle to effective translational research (Simon, 2010).
Acquired resistance to chemotherapeutic drugs remains a major hurdle to effective cancer treatment and eradication, and a better understanding of the genes and pathways that contribute to this is needed.
To outsiders it can seem like magic, but leaders in these organizations take two broad approaches that help professionals get over the initial hurdles to effective collaboration: They act as coaches in order to lower cultural barriers, and they act as architects in order to lower structural barriers.
The phenomenon of acquired endocrine resistance continues to pose a substantial hurdle to the effective treatment of breast cancer since clinical relapse frequently presents as metastases.
From a regulatory perspective, lack of working knowledge and understanding of M&S concepts create an additional hurdle to the effective use and implementation of the approach in regulatory submissions.
These sequence polymorphisms contribute to antibody escape and are therefore a major hurdle to generating an effective AMA1 vaccine (Healer et al., 2004).
The major hurdles to design effective therapeutic strategies for these diseases are: the genetic heterogeneity (a number of distinct mutations affect numerous individual gene), and the tools to turn off mutated genes are inefficient and difficult to be delivered specifically and efficiently to diseased cells.
The high degree of recalcitrance remains a major hurdle to a cost-effective microbial bioconversion of lignocellulosic feedstocks.
Her ongoing research will provide novel insight into the functions of the ECM in modulating the canonically ineffective healing and remodeling cascade; an unknown that has been a hurdle to the development of effective therapeutics.
Currently, there are two major hurdles to achieving clinically effective siRNA-based therapeutics: establishment of an efficient delivery system that transfers the siRNA to the correct tissue(s); and the reduction of unintended immunotoxicity associated with unmodified siRNA.
