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An increase in glucose level was also observed in humans administered with isoflurane, and it is thought that this may be due to a decreased insulin response [35].
The occurrence of tolerance or host desensitization in animals and humans administered multiple doses of microbial products has long been recognized [ 36].
We have shown here that humans administered exogenous dexamethasone exhibit a significant rise in SkM C/EBPβ mRNA levels consistent with the findings of Yang and colleagues [ 16].
Miller et al [ 42] found no elevation in fasting plasma homocysteine concentrations in studies with animals and humans administered vitamin B6 deficient diets.
Conversely, DHA can achieve plasma concentrations of approximately 200 μM in humans administered daily doses of oral DHA preparations over the course of a month [ 75].
Demethylated 2-MeOE1 (2-OHE1) halsolso been measured in the urine of humans administered with [H]2-MeOE2, althisgh this metabolite could not be detected in plasma (Longcope et al, 1980).
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Although there are no studies in humans administering GnRH antagonist followed by kisspeptin, the direct action of kisspeptin on GnRH neurones is inferred from consistent findings in rodents and nonhuman primates.
Therefore, to better approximate METH abuse patterns reported in humans, we administered METH to rats according to a regimen of escalating METH doses followed by multiple drug binges.
In humans, LVS administered by scarification confers excellent protection against systemic challenge with high doses of subspecies tularensis and against lower doses of inhaled bacteria [10].
In humans, exogenously administered IL-6 up to high physiologic circulating levels, causes a decrease in circulating IGF1 [ 26].
Sucralose, a noncalorific artificial sweetener, stimulates GLP-1 in vitro, but apparently has no effect on incretin secretion in healthy humans when administered as a preload (61 61).
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