In an attempt to better reflect the human setting, we applied a relatively mild model of VILI using clinically relevant ventilator settings thereby preventing shock, metabolic acidosis and substantial damage to lung architecture [20].
This underscores in a human setting that leukemia development is a multistep process that requires multiple, consecutive, genetic abnormalities.
Denied a populous human setting with its diversity of wills and motives, a narrative like this can be quickened by a feeling for mood and landscape.
Thus, our conclusions pertaining to anti-TNF therapy are predicated on ETN and antibody-based therapeutics inducing similar inhibitory effects on mTNF in a human setting.
The cosmic setting and concern of the P account is thus followed by the human setting and concern of the J account.
If verified in the human setting, these findings have significant implications for antibody design, biomarker discovery, and the development of synergistic combinatorial therapies.
Before proposing that this material should be used in the human setting a final set of experiments using this scaffold to replace diseased bladder wall is necessary.
These studies inform the rational design of targeted immunotherapies and facilitate translation of mouse functional DC biology to the human setting.
In the interdependent, egalitarian context of the tribe, the ancestral human setting, Wilson says, "it becomes advantageous for members of the team to share information, turning the eyes into organs of communication in addition to organs of vision".
Applied in the human setting this BioArtificial Liver machine could aid the treatment of patients with acute liver failure, allowing time for regeneration of patients' own liver, obviating the need for transplant.
Therefore, biomimetic 3D models of the HSC niche that allow to control HSC behavior in vitro and to test drugs in a human setting are relevant for the clinics and pharmacology.
