Sentence examples for human sensitization from inspiring English sources
The method assumes that LNC proliferative responses are causally and quantitatively associated with the effectiveness of sensitization induction (ECETOC, 2003, 2008), yielding results that quantitatively describe relative sensitizing potency, which correlates with human sensitization thresholds (Loveless et al., 2010; van Loveren et al., 2008).
Human sensitization data often stem from human maximization tests (HMT) [ 16] and human patch tests (HPT).
The incidence of alleged human sensitization to chemicals has increased, in part, due to the fact that chemical companies are moving to larger and/or different markets.
Further research on animal models is warranted; however, presently, animal models cannot provide quantitative data related to thresholds for either human sensitization or elicitation.
The identified markers are involved in biological pathways with immunological relevant functions, which can shed light on the process of human sensitization.
In an extensive report from the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM), the performance characteristics of LLNA were compared to other available animal-based methods and human sensitization data (HMT and HPT) [ 17].
As mechanically insensitive ("sleeping") nociceptors have been shown to mediate the axon-reflex in human skin, sensitization of this class of nociceptors might contribute also to the UV-B-induced primary mechanical hyperalgesia.
DEP was not a dermal sensitizer in healthy human volunteers, although sensitization was reported in some studies, mostly involving persons with skin diseases (Api 2001).
This indicates that the light regulation of thermal somatosensory sensitivity may not exist in healthy humans without prior sensitization or predisposition.
Moreover, there is evidence in mice and humans that allergic sensitization may occur in the prenatal period[7] [9].
Autoimmune disease in humans after active sensitization with brain tissue is a rare event.
