Single-cell whole-genome sequencing (WGS) in >200 single cells, including >160 neurons from three normal and two pathological human brains, sensitively identified germline trisomy of chromosome 18 but found most (≥95%) neurons in normal brain tissue to be euploid.
Conclusions: Gluten-derived peptides could be sensitively detected in human feces in positive correlation with the amount of gluten intake.
Thirdly, we demonstrate in additional case studies that GGEA can be applied to human regulatory pathways, where it sensitively detects very specific regulation processes, which are altered in tumors of the central nervous system.
Ultimately, proposed biosensor was introduced to real human serum samples to determine HSP70 sensitively and accurately.
In response to the anisotropically multiscale patterned topography, the adhesion and differentiation of human mesenchymal stem cells (hMSCs) were sensitively controlled.
Existing serologic and molecular techniques can sensitively and specifically detect human SFV infections (29).
Validation studies showed that hypermethylation or hypomethylation of Alu elements in human cell lines could be detected sensitively by the assay after treatment with 5-aza-dC and M. SssI, respectively.
The book is a blend of eye-opening statistics and candid, often moving, and sensitively told stories about the human beings behind them.
As well as recording natural variability, dust records are also shown to sensitively track the impact of human activity.
The role of hillslopes, functioning as the key elements for sediment production, storage and transfers, is particularly important within headwater systems in cold climate mountain landscapes that are considered to react sensitively to climate change and human impact.
