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Our demonstration that metabolic state influences human risky economic decisions is predicted by biological models accounting for metabolic reference points, but not by normative economic theory.
Recent research has revealed that this information format influences human risky choice and can even reverse risk preferences [ 15– 17].
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Thus, both the risk-sensitive foraging literature and the human risky-choice literature lead us to predict an effect of reward value on risky choice, but the foraging literature predicts an effect on risk sensitivity, whereas the human literature predicts an effect on risk preference.
Importantly, CAR exhibits remarkable species selectivity in its ligand binding and activation profiles, which makes direct extrapolation of findings from mouse to human extremely risky.
In humans, correspondingly, risky decision-making increases when CRT levels are elevated.
Young chimps are excellent models for hepatitis research because they are so genetically close to humans and exhibit the same biochemical changes from the hepatitis viruses, yet they do not contract the clinical disease that makes tests on humans so risky.
As Peretti found out in the early days, VCs see humans as risky.
Their hunch is that hanging around sites visited or altered by humans is risky.
But investing in human capital is risky.
The first human trials are risky and ethically complicated.
"Even very risky human capital is more bondlike than stocklike," Mr. Gordon said.
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