Gerstein, M. B. et al. Architecture of the human regulatory network derived from ENCODE data.
Najafabadi, H. S. et al. C2H2 zinc finger proteins greatly expand the human regulatory lexicon.
Mauri, C. & Menon, M. Human regulatory B cells in health and disease: therapeutic potential.
Presumably human regulatory genes are more sophisticated and can construct greatly more complex structures like the human brain.
Human regulatory T cells (Treg) are able to actively suppress autoreactive immune responses.
Neph, S. et al. An expansive human regulatory lexicon encoded in transcription factor footprints. Nature 489, 83 90 (2012).
Baecher-Allan, C., Wolf, E. & Hafler, D. A. MHC class II expression identifies functionally distinct human regulatory T cells.
Kinnunen, T. et al. Accumulation of peripheral autoreactive B cells in the absence of functional human regulatory T cells.
Sarrabayrouse, G. et al. CD4CD8αα lymphocytes, a novel human regulatory T cell subset induced by colonic bacteria and deficient in patients with inflammatory bowel disease.
Seddiki, N. et al. Expression of interleukin (IL -2 and IL -2receptors discriminands between human regulatory and activated T cells.
Chaturvedi, V., Collison, L. W., Guy, C. S., Workman, C. J. & Vignali, D. A. Cutting edge: Human regulatory T cells require IL-35 to mediate suppression and infectious tolerance.
