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She is analyzing its effects on the prostate in young mice and rats, and also in rats that have been implanted with human prostate cells.
Here, to find novel genes, we analyzed all the transcripts expressed in normal human prostate cells using this microarray.
While PSMA is expressed in normal human prostate cells and certain other normal tissues, it is highly upregulated in PCa, making it a promising diagnostic and therapeutic target [2].
Hence, coupling lensfree microscopy with 3D cell culture provides an innovative tool to study epithelial tissue morphogenesis in a large field of view and to elucidate the regulation of growth, morphogenesis and differentiation in normal and cancerous human prostate cells.
Overexpression of HOXC4, HOXC5, HOXC6 and HOXC8 was also reported to accompany the malignant phenotype in human prostate cells [28].
Recently, M. hyorhinis has been implicated in the transformation of human prostate cells [25] and thus may pose a significant health risk related to carcinogenesis.
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Human prostate cell proliferation in vitro study was attenuated using the ethanol extract of Punica granatum L. var.
The human prostate cell line, DU-145 was maintained in RPMI-1640 medium with 10% foetal bovine serum and 50 μg/ml penicillin/streptomycin.
The biological effects of these compounds on three α1-adrenoceptor subtypes and cancerous human prostate cell lines (PC-3, DU-145, and LNCaP) were determined.
In addition, E2F1 induces tumor cell survival and promotes resistance to drug-induced apoptosis via induction of Egr1 transcription in the human prostate cell lines DU145 and PC3 [63].
Finally, the primary human prostate cell fibroblasts were also cultured in medium with or without DHT for 72 hrs and RNAs were extracted for real-time qPCR analysis.
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