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"There is almost no human outcome you can measure that doesn't have both a genetic and an environmental component.
"We wanted the human outcome and we've got that," he says, gesturing towards people on the phone through the open door of the bland side room we're in.
We came to Hello Lamp Post knowing that all the 'things' were already in place, our challenge was to build a network, one that united all these smart systems for a more human outcome".
Of the 35 CRCTs that reported at least one human outcome, 27 were for interventions in the management of malaria whilst the rest were for managing leishmaniasis (4 trials), lymphatic filariasis (2 trials) and schistosomiasis (2 trials).
However, to date, human outcome studies have been limited by small patient sample sizes (n < 30, a common limitation when studying rare diseases).
It seems to us that increased measurement precision in animal research has somewhat raised expectations regarding human outcome prediction of preclinical data.
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As AI-first replaces mobile centricity with (personalised) user centricity, brands will need to focus on human outcomes.
We might have guessed that the things we invent and design will produce unmistakably human outcomes at some point.
A collaborative study by academics, government, and private corporations found that pharmaceuticals testing in rodents accurately predicts human toxicity less than half the time; a recent publication on inflammatory diseases described mouse models as "close to random" in terms of predicting human outcomes.
Such reactions generally do not preclude clinical development or marketing approval, because it is widely accepted that immune-mediated reactions in nonclinical species are not predictive of human outcomes.
So when you look at people who are very successful or resilient, positive human outcomes come from extremely stable, strong, loving relationships.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com