Sentence examples for human mutations from inspiring English sources

With the exception of CpG mutations, linking the observed non-randomness of human mutations to known sequence-dependent mutational mechanisms remains challenging.

This paper describes how approximately 100 academic biologists tried to trade their data for corporate support of a worldwide Depository for human mutations data.

Pathological human mutations in Piezo1 primarily weaken the inactivation gate and render the channels less sensitive to voltage modulation.

After swarms of human mutations and alien life-forms, borne along on a tide of fireballs, what can cinema still surprise us with?

Human mutations that cause disease through the misrouting of GPCRs including GnRHR are also reviewed.

By inserting copies of the DNA fragment into pigment-producing cells in a laboratory dish, they found that the mutation had the same effect, cutting melanin production, as human mutations did.

Naturally occurring human mutations at the site of conformational change impair the folding of proinsulin and cause permanent neonatal‐onset diabetes mellitus.

It is known that rare human mutations in certain genes in bile acid and bile metabolic pathway influence blood cholesterol levels.

Thus by targeting multiple cancer associated human mutations to the appropriate murine epithelia, mice develop tumours that more closely recapitulate the human disease.

The recapitulation of the unexpected bidirectional expression of the SCA8 expansion in mice demonstrates the power of studying human mutations using large-insert BAC clones to approximate their human genetic context.

In line with the rodent clock gene mutation studies, human mutations in several clock genes were shown to contribute to the genetic susceptibility to obesity, insulin resistance and T2DM.