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Hollywood also turned out "Francis in the Haunted House" (1956), but by then, Mr. O'Connor had decided that a continued association with a mule was not a good thing for his career, and the human lead went to Mickey Rooney.
I didn't care too much for Lou Romano's human lead, Lingiuini, but Peter O'Toole and Ian Holm are in top form as the tiny sous-chef and monstrous food writer, Anton Ego.
While recent attempts to shrink comic-book universes for television have felt tinny and toyish, this one scores by entering the roughed-up, semi-real world of Nolan-era Batman, albeit with its own streak of pulpy venom and an empathetic human lead worth rooting for in Charlie Cox.
Much of what is known about human lead toxicity and its effects is derived from animal studies.
Although it has been hypothesized that hydrofluosilicic acid and sodium silicofluoride might increase human lead uptake from water, a 2006 statistical analysis did not support concerns that these chemicals cause higher blood lead concentrations in children.
Instead, stepping into the "human lead" role for Age of Extinction is Mark Wahlberg, who previously paired with Bay on last year's Pain & Gain (which turned out to be more pain than gain), and whose previous go at a big budget franchise flick didn't work out so well for him (or us, for that matter).
This hypothesis is based on published studies showing elevated blood lead concentrations in subsistence hunter populations, retention of ammunition residues in the tissues of hunter-killed animals, and systemic, cognitive, and behavioral disorders associated with human lead body burdens once considered safe.
The hypothesis that rifle bullet fragments are an additional source of human lead exposure is suggested by radiographic studies of deer killed with standard lead-based bullets, which show hundreds of small metal fragments widely dispersed around wound channels [28] [30].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com