Sentence examples for human fractures from inspiring English sources

NSAIDs are commonly used in the clinic, and there is a general perception that this does not influence healing in common types of human fractures.

BMP-2 has now been approved by the Food and Drug Administration for human fractures (press release, 21 November 2002, Wyeth Pharmaceuticals Inc., Madison, NJ, USA).

Although it may seem that we have kicked in an open door, there are no previously reported data on the histology of healing human fractures in cancellous bone outside the spine.

This might explain the perplexing discrepancy between the seemingly harmless clinical use of NSAIDs in patients with fractures, and the clearly detrimental effect of such treatment in animal models, as human fractures usually occur in metaphyses, while almost all animal models deal with shaft fractures.

A study showed a relation between human fracture healing at the 16th week and a decline in serum osteocalcin (OC) and alkaline phosphatase (AP) [11].

During the early phase VEGF (vascular endothelial growth factor) is upregulated (Lienau et al. 2009), which is in concurrence with the high VEGF concentrations in human fracture haematoma (Street et al. 2000).

In human fracture haematoma, an upregulation of the osteogenic factors SPP1 (secreted phosphoprotein 1 / osteopontin) and RunX2 (runt-related transcription factor 2) observed within the first 72 h supports the fact that bone formation is already initiated during the haematoma phase of fracture healing (Kolar et al. 2011; Schmidt-Bleek et al. 2012a).

Short bones such as carpal and tarsal bones, the main targets for the SMA staple fixation in human fracture scenarios, consist primarily of cancellous bone and as such make PU foam an ideal candidate for clinical replication (Bechtold et al. 1993; Qin 2013; Rovinsky et al. 2000).

Our study was mainly concerned with the effects of PTH on human fracture repair.

The future will tell about the results of ongoing human fracture trials with sclerostin antibodies.

Further studies with longitudinal design would help understanding the role of these markers in human fracture healing.