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Some Baptists lay stress upon having no human founder, no human authority, and no human creed.
If a corporation can mirror its human founder, Apple probably does that better than almost any other.
To examine the possibility that outbred CD-1 mice model human founder populations, we compared the average MAF differences observed among subpopulations of CD-1 mice to a previous study of human populations (Figure 6).
We have determined that CD-1 mice are polymorphic at a significant number of loci, are reasonably outbred, and have a complex genetic history similar to a human founder population.
Although outbred mice are commonly cited as models for outbred human populations [1], [2], [3], based on their histories, it is more likely that outbred mice reflect human founder populations rather than outbred human populations.
We anticipate that it will soon be possible to apply these methods to precisely estimate the variance from pairwise interactions in human founder populations.
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