Sentence examples for human efflux from inspiring English sources

Strikingly, bacterial efflux pump LmrA was able to functionally complement human efflux pump P-glycoprotein in human lung fibroblast cells [ 15].

Therefore and in light of accumulation of the musks in human tissue research is needed to determine if the musks similarly inhibit the human efflux transporters, thereby compromising this defense against toxicants.

We have identified amino acids in a human drug efflux pump that affect interaction with substrate and protein targeting.

The first eukaryotic ABC transporter discovered was the human (h) drug efflux transporter MDR (multidrug resistance) P-glycoprotein (hABCB1/MDR1), the name of which reflects that its expression in cancers can cause a decreased cellular drug accumulation (initially referred to as drug permeability, 'P'), resulting in the resistance of tumours against chemotherapy [ 14, 15].

A recent study in humans demonstrates the efflux of Aβ from the brain to the plasma [ 36].

Laforenza, U., Scaffino, M. F. & Gastaldi, G. Aquaporin-10 represents an alternative pathway for glycerol efflux from human adipocytes.

Overexpression of STARD3 increased ABCA1 protein levels, and cholesterol efflux in human THP-1 macrophages (Borthwick et al., 2010) and increased lipidation of exogenous apoA-I in McRH-7777 hepatoma cells (Soffientini et al., 2014).

Taken together, these findings suggest that VCC-formed channels can support additional apical chloride efflux from human colon tissue samples.

To measure cytotoxicity during bacterial efflux, 5637 human bladder cells were infected with WT or knockout UPEC strains for an efflux assay as described above.

Furthermore, functionality of HDL with respect to inducing cholesterol efflux from human monocyte cells (THP-1) was determined.

Collectively, these data indicate that the miR206 LXRα pathway is functional and of potential physiological relevance in facilitating cholesterol efflux from human macrophages.