Exact(4)
Animal models may provide insight into the mechanisms involved, but do not necessarily provide accurate representations of the human condition, making human diffusion MRI studies with direct histological confirmation crucial for our understanding of tissue changes secondary to neurodevelopment and disease.
This limitation also applies in the investigation of the association between interhemispheric asymmetry and handedness [28], [87] and might explains the discrepancy between our results and those in one human diffusion MRI study including both male and female subjects [29].
Labelling of white matter anatomical structures was done by overlaying the significant clusters with standard-space white matter tracts probabilistically defined from a human diffusion tensor imaging atlas (Thiebaut de Schotten et al., 2011).
At an isotropic voxel size of 43 µm, the spatial resolution is approximately 30 000 times higher resolution than a typical human diffusion MRI scan, and 10 times higher after accounting for the approximately 3000-fold dinference in total brain volume (Herculano-Houzel 2009).
Similar(56)
Fiber architectures were computed from human forearm diffusion tensor data using extracted primary eigenvectors and the denoised data.
Recent developments in MRI technology, however, have enabled the study of the anatomical basis of cerebellar circuits in humans using diffusion tensor imaging (DTI) methodology.
Recent developments in MRI technology have enabled the study of the anatomical cerebellar connections in vivo in humans using diffusion tensor imaging (DTI) and tractography (Habas and Cabanis 2007a, b; Jissendi et al. 2008; Doron et al. 2010; Anderson et al. 2011; Hyam et al. 2012).
In particular, dorsal premotor regions seem to connect predominantly to the superior parietal cortex and subserve reaching in space while more ventral aspects of the premotor cortex interact more strongly with the intraparietal sulcus for object manipulation, a finding that has more recently been corroborated in humans using diffusion tractography (Tomassini et al. 2007).
Piroxicam and human serum albumin diffusion in Pluronic F127 hydrogel was monitored by measuring the absorbance of light passing through the diffusion cell at 26 °C, thus providing real-time concentration maps (7 × 3 mm imaging area) within the gel as a function of time.
This approach has non-invasively been demonstrated in the human brain with diffusion tensor tractography.
Instead, the radiation model considers human movements as diffusion processes that depend on the population distribution over the space, reproducing Stouffer's theory of intervening opportunities [17].
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