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We suspect that it will be difficult for the models to achieve the additivity of rates that is so robust in the human data presented here.
Also, the descriptive human data presented here demonstrated that LG can be detected in children's urine samples.
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All human pathway data presented here were downloaded from four primary data repositories, BioCarta, WikiPathways, NCBI BioSystems and Pathway Commons representing six data sets (update to February 2012).
In the human population data presented here, the association of PFOS concentration with increasing trans-aminase is almost as prominent as the association for PFOA, and human laboratory cell data indicate relatively lower response of liver cells to PFOS than to PFOA (Wolf et al. 2008).
Although it has been hypothesized that adaptation of the BSE agent through secondary passage in humans may result in a greater risk of onward transmission due to an increased virulence of the agent for humans, our data presented here in two murine models suggest no significant alterations to transmission efficiency of the agent following human-to-human transmission of vCJD.
Although data obtained in animals may not translate perfectly to humans, the data presented here do cause some concern for the current conditions of BPA use, exposure, and regulation.
Results obtained with mice do not necessarily translate to humans; nevertheless, data presented here strongly suggest that potent influenza A virus-specific CD8+ T cell responses cause fatal immunopathology in aged mice.
As we explore the contributions of viruses to the human microbiome, the data presented here suggest varying expression of bacteriophage communities in oral health and disease.
Although additional work is required to define the drug-like properties of Gamitrinibs in anticipation of human testing, the data presented here suggest that selective suppression of mitochondrial Hsp90s may provide novel molecular therapy in prostate cancer, and improve the currently limited activity of Hsp90-based therapy in these patients (Trepel et al, 2010).
There is strong evidence that Zip13 primarily transports zinc not iron when expressed in human cells, and the data presented here do not refute those studies.
Consistent with our previous observation that the pathogenesis of MexTAg mesothelioma development closely resembles human mesothelioma development, the data presented here further validate the use of the MexTAg model for investigating mesothelioma.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com