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In this paper, we present 3D vascular imaging of living human cavity tissues using the modified OCT microangiography method.
Notwithstanding, there has been limited discussion regarding the assessment of micro vasculature in the human cavity tissues.
To our best knowledge, this is the first OCT angiography study for revealing vascular anatomy of the wide-range of oral and nasal human cavity tissues in vivo.
This study showed the feasibility of OCT microangiography for imaging the microcirculation perfused within ~2 mm in depth from the tissue surface of human cavity in vivo.
The initial findings in this current study showed a great potential of our instrument for mapping 3D microcirculation of the functional vessels in a variety of human cavity tissues including the labial tissue.
We report three-dimensional (3D) imaging of microcirculation within human cavity tissues in vivo using a high-speed swept-source optical coherence tomography (SS-OCT) at 1300 nm with a modified probe interface.
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Diseases in human cavities such as mouth and nose are a prevalent and significant health care problem worldwide.
Statistically significant differences in these multi-parametric values have been found between healthy and diseased tissues within human cavities [ 2, 18, 19].
However, these prior studies have failed to reconstruct the complex microvasculatures of the human cavities either due to the difficulty faced with the accessibility of the inner cavity with the forward imaging probe or due to the unavailability of the techniques suitable for purely extracting the vasculature.
Fluorescence imaging of the human oral cavity using hypericin has great potential as a complementary technique to standard white light examination and histopathology of oral cavity lesions.
There are an estimated 600 species of bacteria that normally inhabit the human oral cavity.
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