Sentence examples for human aggregation from inspiring English sources

Human curation, human aggregation.

We next adapted this technology to conduct a small molecule screen and identified compounds that altered the intracellular accumulation of the human aggregation prone mutant that causes liver disease in α1-antitrypsin deficiency.

The described technique is well-suited to study the quaternary structure of other human aggregation-prone proteins under physiological conditions.

In humans, aggregation-causing mutations in Q/N-rich proteins have been linked to various degenerative diseases, including ALS.

G1 G7 were also effective inhibitors of AA-induced human platelet aggregation.

All new compounds have been evaluated as inhibitors of human platelet aggregation induced by the PAR1 agonist SFLLRN.

All new compounds were screened as inhibitors of human platelet aggregation induced by the PAR1 agonist SFLLRN and as cytotoxic agents in human cancer cell lines.

The present study aimed to evaluate the influence of pig genetic modification on human platelet aggregation induced by pig endothelial cells (EC).

These compounds with m-substituted group (5, 7, 9) showed a higher IC50 value for inhibiting ADP-induced human platelet aggregation than those with o-substituted group (4, 6) or p-substituted group (3, 8).

The missing VIV11VV7 oxidation-state member of the polyoxooctadecavanadate(IV/V) — azide family of inorganic host-guest systems has been incorporated in a NaI-containing 3D architecture; the complex shows remarkable inhibition properties on human platelet aggregation and antitumoural activity against cancer cell lines.

We have combined a high throughput RNAi screen with in vivo candidate validation to identify potential new regulators of mutant human Htt aggregation.