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In its extreme form the frozen accident theory proposes that the assignment of codons/anticodons to amino acids was completely random, but once made was locked in place due to the hugely deleterious effect any changes would have had on cell proteins.
Similar(59)
"It had a deleterious impact".
Hugely so.
Hugely informative.
A | Hugely.
That's hugely gratifying.
Hugely recommended.
Hugely expensive.
Hugely courageous.
I feel hugely at peace.
Herring is hugely prolific.
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