Regarding its influence on the coagulation system, 6% HES 130 0.4 may be as safe as gelatine in patients with blood loss and huge volume substitution.
That substitution, met with huge cheers from the Villa supporters, looked like paying off in the 64th minute when Leandro Bacuna escaped in space on the right flank and delivered an inviting cross that picked out the Belgium international.
As pointed out in the previous section, wage subsidies entail huge indirect effects, especially deadweight, substitution and displacement, making them cost-ineffective and undesirable due to their long-run implications on skills development67.
Of course, this "e-substitution" represents a huge technological challenge, but let us not draw only negative conclusions.
The apatite group minerals with the general formula M5(PO4)3X have a wide compositional variation because of their huge isomorphic capacity and numerous substitutions of ions [1 5], which play an important role in many research areas, such as geology, environmental sciences, biomaterials, material science and technology [6 9].
Before reaching a level comparable to that of wild-type phage, the fitness must increase by 7.6, which requires a huge library size if only substitutions are employed, as discussed below.
Brazilian consumers pay a huge price for the crony capitalist policy of import substitution.
The static condensation algorithm with a substitution matrix manipulation is employed to handle the huge matrices without any numerical restriction.
Understanding protein homology within such huge sets of sequences requires tracing the divergence by mutation, substitution, insertion and deletion of residues.
Liu et al. [ 14] applied huge amounts of sequence, analyzing 40,925 amino acids with a substitution model intended to minimize long-branch attraction problems.
