Exact(2)
Requirement of huge amount of sample and inability to detect low abundance proteins is also a major drawback.
Although the major limitations of 2-DE still apply to 2D-DIGE, but the introduction of more sensitive 2-D DIGE technique has overcome most of the limitations such as requirement of huge amount of sample and inability to detect low abundance proteins.
Similar(58)
To solve the problem of computational complexity of the huge amount of data samples we moved from time domain to frequency domain.
To solve the problem of computational complexity due to the huge amount of data samples (>600 millions of Call Data Records) we moved from the time domain of communication patterns to the frequency domain, applying the Fast Fourier Transform algorithm to each group of daily time series.
However, in a cloud radio access network (C-RAN) with massive MIMO, operation of many antennas incurs a huge amount of digital sampled data to be transported over the fronthaul link between a baseband unit (BBU) pool and each remote radio head (RRH).
Often it is the only feasible method to handle the huge amount of insect specimens typically sampled in biodiversity studies, where a 'true' taxonomic identification, which mostly would involve dissection and the time-intensive use of identification keys, would be impossible (e.g. [35] [37]).
The Marquette poll, which received a huge amount of attention, had a small sample size and a large margin of error.
First, because the huge amount of bacteria present in the sample, and also, because the bacteria lysis induced by bacteriophage excision.
This large increase can be explained by the huge amount of variability found when ignoring the sexual differences between gametic tissues in gonozooid samples.
Coaches deserve a huge amount of credit.
That's a huge amount of damages.
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